Payloads: Cardinal Heart 2.0: Microscopy and video recordings were performed on eight BioCell tissue chambers. A previous investigation showed that four weeks of microgravity exposure caused significant changes in heart cell function and gene expression that could lead to long-term damage or cardiac muscle atrophy. Effect of Microgravity on Drug Responses Using Heart Organoids (Cardinal […]

Payloads: Cardinal Heart 2.0: A media change was performed for Samples 1B and 1A. A previous investigation showed that four weeks of microgravity exposure caused significant changes in heart cell function and gene expression that could lead to long-term damage or cardiac muscle atrophy. Effect of Microgravity on Drug Responses Using Heart Organoids (Cardinal Heart […]

Payloads: Cardinal Heart 2.0: Samples were removed from the Glacier facility. A previous investigation showed that four weeks of microgravity exposure caused significant changes in heart cell function and gene expression that could lead to long-term damage or cardiac muscle atrophy. Effect of Microgravity on Drug Responses Using Heart Organoids (Cardinal Heart 2.0) uses heart […]

Payloads: Engineered Heart Tissue-2: The appropriate hardware was gathered in preparation for the upcoming EHT-2 experiment operations. A Human iPSC-based 3D Microphysiological System for Modeling Cardiac Dysfunction in Microgravity-2 (Engineered Heart Tissues-2) continues work with 3D cultured cardiac muscle tissue to assess human cardiac function in microgravity. Previous work with 3D cultures in space detected […]

SpaceX-27 (SpX-27) Docking: The SpX-27 Cargo Dragon docked to the ISS at 6:31 AM CT, delivering more than 6,200 pounds of cargo. Since its launch Tuesday evening, the spacecraft has successfully performed a series of maneuvers to setup today’s docking to the Node 2 (Harmony Module) forward port of the ISS. Payloads: Analyzing Interferometer for […]

Payloads: Combustion Integrated Rack/Solid Fuel Ignition and Extinction/Growth and Extinction Limit (CIR/SoFIE/GEL): In support of ongoing science, the crew accessed the CIR and exchanged a used manifold gas bottle with a new bottle. SoFIE is a hardware insert for the CIR that enables a wide range of solid-material combustion and fire suppression studies, providing common […]

Payloads: Immunity Assay: In continuation of the multi-day experiment session, science samples were processed in the Human Research Facility (HRF) centrifuge. The Monitoring the Cellular Immunity by In Vitro Delayed Type Hypersensitivity (DTH) Assay on the ISS (Immunity Assay) investigation aims to monitor the impact of spaceflight stressors on cellular immune functions in a blood sample, with […]

Payloads: Electrostatic Levitation Furnace (ELF): The ELF high-speed camera LAN cable was routed to avoid interference with the work volume and small experiment area doors. The high-speed camera was recently installed and checked out to allow additional capabilities for the facility. ELF is an experimental facility designed to levitate/melt/solidify materials by containerless processing techniques using […]

Payloads: Astrobee: The Astrobee systems were powered on and stowage in the area cleared away to allow Astrobee to perform free-flight maneuvers. This type of activity is commonly called “crew minimal” and the goal is for the ground to command the Astrobee experiment systems to complete the session objectives with minimal crew involvement.  Astrobee is […]

Payloads: Human Research Program (HRP) sample collection: The crew collected multiple body samples in support of the Food Physiology, Repository, Host Pathogen, and Standard Measures investigations.  Food Physiology is designed to characterize the key effects of an enhanced spaceflight diet on immune function, the gut microbiome, and nutritional status indicators. Repository is a storage bank […]